产品分类

亮丙瑞林|(Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH acetate salt|Pyr-His-Trp-Ser-Tyr-(D-Leu)-Leu-Arg-Pro-NHEt|53714-56-0|74381-53-6

产品编号：SR024（醋酸盐和TFA盐对应2中不同的盐形式cas不同）
名称：亮丙瑞林|(Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH acetate salt|Pyr-His-Trp-Ser-Tyr-(D-Leu)-Leu-Arg-Pro-NHEt|53714-56-0|74381-53-6
序列：Pyr-His-Trp-Ser-Tyr-(D-Leu)-Leu-Arg-Pro-NHEt
纯度：≥95% (HPLC)
分子式：C61H88N16O14|C59H84N16O12
分子量：1269.450|1209.4
外观：白色粉末
CAS#：53714-56-0(Acetate)|74381-53-6(TFA)
储存条件：Store at -20°C
溶解性：Soluble to 1 mg/ml in water

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亮丙瑞林生物活性

描述	Leuprolide acetate是一种有效的促性腺激素释放激素 (GNRH)受体激动剂，用于治疗前列腺癌，子宫内膜异位症，子宫肌瘤。
相关类别	多肽产品研究领域 >> 内分泌
参考文献	[1]. Mizutani T, Sugihara A, Nakamuro K, Suppression of cell proliferation and induction of apoptosis in uterine leiomyoma by gonadotropin-releasing hormone agonist (leuprolide acetate). J Clin Endocrinol Metab. 1998 Apr;83(4):1253-5. [2]. Silva AL, Abreu LG, Rosa-e-Silva AC, Leuprolide acetate reduces both in vivo and in vitro ovarian steroidogenesis in infertile women undergoing assisted reproduction. Steroids. 2008 Dec 22;73(14):1475-84. [3]. Guzmán-Soto I, Salinas E, Hernández-Jasso I, Leuprolide acetate, a GnRH agonist, improves experimental autoimmune encephalomyelitis: a possible therapy for multiple sclerosis. Neurochem Res. 2012 Oct;37(10):2190-7. [4]. Gaikwad U, Parle M, Kumar A, Effect of ritanserin and leuprolide alone and combined on marble-burying behavior of mice. Acta Pol Pharm. 2010 Sep-Oct;67(5):523-7

描述

Leuprolide acetate是一种有效的促性腺激素释放激素 (GNRH)受体激动剂，用于治疗前列腺癌，子宫内膜异位症，子宫肌瘤。